The TILO railway company provides fast and easy connections between the main centers of Ticino and in direction Lombardy. The TILO network consists of the lines:
- S10 Bellinzona-Lugano-Chiasso-Como
- S20 Biasca-Bellinzona-Locarno
- S30 Cadenazzo-Luino-Malpensa
- S40 Varese-Mendrisio-Como
- S50 Varese-Mendrisio-Lugano- Bellinzona.
The offer is supplemented by the RE10 Erstfeld-Bellinzona-Lugano-Milano connections. There is also a night offer: the TILO Pigiama service is available on the nights Friday/Saturday and Saturday/Sunday on the lines S10 and S20 in Ticino.